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dc.contributor.authorHagedoorn, N.N.
dc.contributor.authorZachariasse, J.M.
dc.contributor.authorBorensztajn, D.
dc.contributor.authorAdriaansens, E.
dc.contributor.authorVon Both, U.
dc.contributor.authorCarrol, E.D.
dc.contributor.authorEleftheriou, I.
dc.contributor.authorEmonts, M.
dc.contributor.authorVan Der Flier, M.
dc.contributor.authorDe Groot, R.
dc.contributor.authorHerberg, J.A.
dc.contributor.authorKohlmaier, B.
dc.contributor.authorLim, E.
dc.contributor.authorMacOnochie, I.
dc.contributor.authorMartinón Torres, Federico 
dc.contributor.authorNijman, R.G.
dc.contributor.authorPokorn, M.
dc.contributor.authorRivero Calle, Irene
dc.contributor.authorTsolia, M.
dc.contributor.authorZavadska, D.
dc.contributor.authorZenz, W.
dc.contributor.authorLevin, M.
dc.contributor.authorVermont, C.
dc.contributor.authorMoll, H.A.
dc.date.accessioned2024-12-27T09:02:14Z
dc.date.available2024-12-27T09:02:14Z
dc.date.issued2022
dc.identifier.issn1468-2044
dc.identifier.urihttp://hdl.handle.net/20.500.11940/19306
dc.description.abstractObjective (1) To derive reference values for the Shock Index (heart rate/systolic blood pressure) based on a large emergency department (ED) population of febrile children and (2) to determine the diagnostic value of the Shock Index for serious illness in febrile children. Design/setting Observational study in 11 European EDs (2017-2018). Patients Febrile children with measured blood pressure. Main outcome measures Serious bacterial infection (SBI), invasive bacterial infection (IBI), immediate life-saving interventions (ILSIs) and intensive care unit (ICU) admission. The association between high Shock Index (>95th centile) and each outcome was determined by logistic regression adjusted for age, sex, referral, comorbidity and temperature. Additionally, we calculated sensitivity, specificity and negative/positive likelihood ratios (LRs). Results Of 5622 children, 461 (8.2%) had SBI, 46 (0.8%) had IBI, 203 (3.6%) were treated with ILSI and 69 (1.2%) were ICU admitted. High Shock Index was associated with SBI (adjusted OR (aOR) 1.6 (95% CI 1.3 to 1.9)), ILSI (aOR 2.5 (95% CI 2.0 to 2.9)), ICU admission (aOR 2.2 (95% CI 1.4 to 2.9)) but not with IBI (aOR: 1.5 (95% CI 0.6 to 2.4)). For the different outcomes, sensitivity for high Shock Index ranged from 0.10 to 0.15, specificity ranged from 0.95 to 0.95, negative LRs ranged from 0.90 to 0.95 and positive LRs ranged from 1.8 to 2.8. Conclusions High Shock Index is associated with serious illness in febrile children. However, its rule-out value is insufficient which suggests that the Shock Index is not valuable as a screening tool for all febrile children at the ED.
dc.language.isoenes
dc.rightsAtribución 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleShock Index in the early assessment of febrile children at the emergency department: A prospective multicentre study
dc.typeJournal Articlees
dcterms.bibliographicCitationHagedoorn NN, Zachariasse JM, Borensztajn D, Adriaansens E, Von Both U, Carrol ED, et al. Shock Index in the early assessment of febrile children at the emergency department: A prospective multicentre study. Archives of Disease in Childhood. 2022;107(2):116-22.
dc.authorsophosHagedoorn, H. A. N. N.;Zachariasse, J. M.;Borensztajn, D.;Adriaansens, E.;Von Both, U.;Carrol, E. D.;Eleftheriou, I.;Emonts, M.;Van Der Flier, M.;De Groot, R.;Herberg, J. A.;Kohlmaier, B.;Lim, E.;MacOnochie, I.;Martinón-Torres, F.;Nijman, R. G.;Pokorn, M.;Rivero-Calle, I.;Tsolia, M.;Zavadska, D.;Zenz, W.;Levin, M.;Vermont, C.;Moll
dc.identifier.doi10.1136/ARCHDISCHILD-2020-320992
dc.identifier.sophos60e6a17d4edb8e25f92cd984
dc.issue.number2
dc.journal.titleArchives of Disease in Childhood
dc.page.initial116
dc.page.final122
dc.relation.publisherversionhttps://adc.bmj.com/content/archdischild/107/2/116.full.pdfes
dc.rights.accessRightsopenAccess
dc.subject.keywordAS Santiagoes
dc.subject.keywordCHUSes
dc.subject.keywordIDISes
dc.volume.number107


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