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dc.contributor.authorAli, A. M.
dc.contributor.authorSchmidt, M. K.
dc.contributor.authorBolla, M. K.
dc.contributor.authorWang, Q.
dc.contributor.authorGago-Dominguez, M.
dc.contributor.authorCastelao, J. E.
dc.contributor.authorCarracedo, A.
dc.contributor.authorGarzón, V. M.
dc.contributor.authorBojesen, S. E.
dc.contributor.authorNordestgaard, B. G.
dc.contributor.authorFlyger, H.
dc.contributor.authorChang-Claude, J.
dc.contributor.authorVrieling, A.
dc.contributor.authorRudolph, A.
dc.contributor.authorSeibold, P.
dc.contributor.authorNevanlinna, H.
dc.contributor.authorMuranen, T. A.
dc.contributor.authorAaltonen, K.
dc.contributor.authorBlomqvist, C.
dc.contributor.authorMatsuo, K.
dc.contributor.authorIto, H.
dc.contributor.authorIwata, H.
dc.contributor.authorHorio, A.
dc.contributor.authorJohn, E. M.
dc.contributor.authorSherman, M.
dc.contributor.authorLissowska, J.
dc.contributor.authorFigueroa, J.
dc.contributor.authorGarcia-Closas, M.
dc.contributor.authorAnton-Culver, H.
dc.contributor.authorShah, M.
dc.contributor.authorHopper, J. L.
dc.contributor.authorTrichopoulou, A.
dc.contributor.authorBueno-de-Mesquita, B.
dc.contributor.authorKrogh, V.
dc.contributor.authorWeiderpass, E.
dc.contributor.authorAndersson, A.
dc.contributor.authorClavel-Chapelon, F.
dc.contributor.authorDossus, L.
dc.contributor.authorFagherazzi, G.
dc.contributor.authorPeeters, P. H.
dc.contributor.authorOlsen, A.
dc.contributor.authorWishart, G. C.
dc.contributor.authorEaston, D. F.
dc.contributor.authorBorgquist, S.
dc.contributor.authorOvervad, K.
dc.contributor.authorBarricarte, A.
dc.contributor.authorGonzález, C. A.
dc.contributor.authorSánchez, M. J.
dc.contributor.authorAmiano, P.
dc.contributor.authorRiboli, E.
dc.contributor.authorKey, T.
dc.contributor.authorPharoah, P. D.
dc.date.accessioned2017-06-07T07:15:49Z
dc.date.available2017-06-07T07:15:49Z
dc.date.issued2014
dc.identifier.issn1055-9965
dc.identifier.urihttp://hdl.handle.net/20.500.11940/4480
dc.description.abstractEvidence for an association of alcohol consumption with prognosis after a diagnosis of breast cancer has been inconsistent. We have reviewed and summarized the published evidence and evaluated the association using individual patient data from multiple case cohorts.|A MEDLINE search to identify studies published up to January 2013 was performed. We combined published estimates of survival time for "moderate drinkers" versus nondrinkers. An analysis of individual participant data using Cox regression was carried out using data from 11 case cohorts.|We identified 11 published studies suitable for inclusion in the meta-analysis. Moderate postdiagnosis alcohol consumption was not associated with overall survival [HR, 0.95; 95% confidence interval (CI), 0.85-1.05], but there was some evidence of better survival associated with prediagnosis consumption (HR, 0.80; 95% CI, 0.73-0.88). Individual data on alcohol consumption for 29,239 cases with 4,839 deaths were available from the 11 case cohorts, all of which had data on estrogen receptor (ER) status. For women with ER-positive disease, there was little evidence that pre- or postdiagnosis alcohol consumption is associated with breast cancer-specific mortality, with some evidence of a negative association with all-cause mortality. On the basis of a single study, moderate postdiagnosis alcohol intake was associated with a small reduction in breast cancer-specific mortality for women with ER-negative disease. There was no association with prediagnosis intake for women with ER-negative disease.|There was little evidence that pre- or post-diagnosis alcohol consumption is associated with breast cancer-specific mortality for women with ER-positive disease. There was weak evidence that moderate post-diagnosis alcohol intake is associated with a small reduction in breast cancer-specific mortality in ER-negative disease.|Considering the totality of the evidence, moderate postdiagnosis alcohol consumption is unlikely to have a major
dc.language.isoeng
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAlcohol Drinking
dc.subject.meshBreast Neoplasms
dc.subject.meshCohort Studies
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMiddle Aged
dc.subject.meshPrognosis
dc.subject.meshRisk Factors
dc.subject.meshYoung Adult
dc.titleAlcohol consumption and survival after a breast cancer diagnosis: a literature-based meta-analysis and collaborative analysis of data for 29,239 cases
dc.typeArtigoes
dc.authorsophosAli, A. M.
dc.authorsophosSchmidt, M. K.
dc.authorsophosBolla, M. K.
dc.authorsophosWang, Q.
dc.authorsophosGago-Dominguez, M.
dc.authorsophosCastelao, J. E.
dc.authorsophosCarracedo, A.
dc.authorsophosGarzón, V. M.
dc.authorsophosBojesen, S. E.
dc.authorsophosNordestgaard, B. G.
dc.authorsophosFlyger, H.
dc.authorsophosChang-Claude, J.
dc.authorsophosVrieling, A.
dc.authorsophosRudolph, A.
dc.authorsophosSeibold, P.
dc.authorsophosNevanlinna, H.
dc.authorsophosMuranen, T. A.
dc.authorsophosAaltonen, K.
dc.authorsophosBlomqvist, C.
dc.authorsophosMatsuo, K.
dc.authorsophosIto, H.
dc.authorsophosIwata, H.
dc.authorsophosHorio, A.
dc.authorsophosJohn, E. M.
dc.authorsophosSherman, M.
dc.authorsophosLissowska, J.
dc.authorsophosFigueroa, J.
dc.authorsophosGarcia-Closas, M.
dc.authorsophosAnton-Culver, H.
dc.authorsophosShah, M.
dc.authorsophosHopper, J. L.
dc.authorsophosTrichopoulou, A.
dc.authorsophosBueno-de-Mesquita, B.
dc.authorsophosKrogh, V.
dc.authorsophosWeiderpass, E.
dc.authorsophosAndersson, A.
dc.authorsophosClavel-Chapelon, F.
dc.authorsophosDossus, L.
dc.authorsophosFagherazzi, G.
dc.authorsophosPeeters, P. H.
dc.authorsophosOlsen, A.
dc.authorsophosWishart, G. C.
dc.authorsophosEaston, D. F.
dc.authorsophosBorgquist, S.
dc.authorsophosOvervad, K.
dc.authorsophosBarricarte, A.
dc.authorsophosGonzález, C. A.
dc.authorsophosSánchez, M. J.
dc.authorsophosAmiano, P.
dc.authorsophosRiboli, E.
dc.authorsophosKey, T.
dc.authorsophosPharoah, P. D.
dc.identifier.doi10.1158/1055-9965.EPI-13-0901
dc.identifier.isi345270800005
dc.identifier.pmid24636975
dc.identifier.sophos14546
dc.issue.number6
dc.journal.titleCANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
dc.organizationConsellería de Sanidade::Fundación pública Galega de Medicina Xenómica
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Vigo::IBI - Instituto de Investigación Biomédica de Ourense, Pontevedra y Vigo
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago::IDIS.- Instituto de investigaciones sanitarias de Santiago
dc.page.initial934
dc.page.final45
dc.rights.accessRightsopenAccess
dc.typesophosArtículo Original
dc.volume.number23


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