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dc.contributor.authorMuller, T. D.
dc.contributor.authorNogueiras Pozo, Rubén
dc.contributor.authorAndermann, M. L.
dc.contributor.authorAndrews, Z. B.
dc.contributor.authorAnker, S. D.
dc.contributor.authorArgente, J.
dc.contributor.authorBatterham, R. L.
dc.contributor.authorBenoit, S. C.
dc.contributor.authorBowers, C. Y.
dc.contributor.authorBroglio, F.
dc.contributor.authorCasanueva Freijo, Felipe 
dc.contributor.authorD'Alessio, D.
dc.contributor.authorDepoortere, I.
dc.contributor.authorGeliebter, A.
dc.contributor.authorGhigo, E.
dc.contributor.authorCole, P. A.
dc.contributor.authorCowley, M.
dc.contributor.authorCummings, D. E.
dc.contributor.authorDagher, A.
dc.contributor.authorDiano, S.
dc.contributor.authorDickson, S. L.
dc.contributor.authorDiéguez González, Carlos
dc.contributor.authorGranata, R.
dc.contributor.authorGrill, H. J.
dc.contributor.authorGrove, K.
dc.contributor.authorHabegger, K. M.
dc.contributor.authorHeppner, K.
dc.contributor.authorHeiman, M. L.
dc.contributor.authorHolsen, L.
dc.contributor.authorHolst, B.
dc.contributor.authorInui, A.
dc.contributor.authorJansson, J. O.
dc.contributor.authorKirchner, H.
dc.contributor.authorKorbonits, M.
dc.contributor.authorLaferrere, B.
dc.contributor.authorLeRoux, C. W.
dc.contributor.authorLopez, M.
dc.contributor.authorMorin, S.
dc.contributor.authorNakazato, M.
dc.contributor.authorNass, R.
dc.contributor.authorPerez-Tilve, D.
dc.contributor.authorPfluger, P. T.
dc.contributor.authorSchwartz, T. W.
dc.contributor.authorSeeley, R. J.
dc.contributor.authorSleeman, M.
dc.contributor.authorSun, Y.
dc.contributor.authorSussel, L.
dc.contributor.authorTong, J.
dc.contributor.authorThorner, M. O.
dc.contributor.authorvan der Lely, A. J.
dc.contributor.authorvan der Ploeg, L. H. T.
dc.contributor.authorZigman, J. M.
dc.contributor.authorKojima, M.
dc.contributor.authorKangawa, K.
dc.contributor.authorSmith, R. G.
dc.contributor.authorHorvath, T.
dc.contributor.authorTschop, M. H.
dc.date.accessioned2017-06-07T07:33:30Z
dc.date.available2017-06-07T07:33:30Z
dc.date.issued2015
dc.identifier.issn2212-8778
dc.identifier.urihttp://hdl.handle.net/20.500.11940/7923
dc.description.abstractBACKGROUND: The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor. Increasing evidence supports more complicated and nuanced roles for the hormone, which go beyond the regulation of systemic energy metabolism. SCOPE OF REVIEW: In this review, we discuss the diverse biological functions of ghrelin, the regulation of its secretion, and address questions that still remain 15 years after its discovery. MAJOR CONCLUSIONS: In recent years, ghrelin has been found to have a plethora of central and peripheral actions in distinct areas including learning and memory, gut motility and gastric acid secretion, sleep/wake rhythm, reward seeking behavior, taste sensation and glucose metabolism.
dc.language.isoeng
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/cc-by-nc-nd/4.0/
dc.subject.meshGhrelin
dc.subject.meshGrowth hormone segretagogue receptor
dc.titleGhrelin
dc.typeArtigoes
dc.authorsophosMuller, T. D.
dc.authorsophosNogueiras, R.
dc.authorsophosAndermann, M. L.
dc.authorsophosAndrews, Z. B.
dc.authorsophosAnker, S. D.
dc.authorsophosArgente, J.
dc.authorsophosBatterham, R. L.
dc.authorsophosBenoit, S. C.
dc.authorsophosBowers, C. Y.
dc.authorsophosBroglio, F.
dc.authorsophosCasanueva, F. F.
dc.authorsophosD'Alessio, D.
dc.authorsophosDepoortere, I.
dc.authorsophosGeliebter, A.
dc.authorsophosGhigo, E.
dc.authorsophosCole, P. A.
dc.authorsophosCowley, M.
dc.authorsophosCummings, D. E.
dc.authorsophosDagher, A.
dc.authorsophosDiano, S.
dc.authorsophosDickson, S. L.
dc.authorsophosDieguez, C.
dc.authorsophosGranata, R.
dc.authorsophosGrill, H. J.
dc.authorsophosGrove, K.
dc.authorsophosHabegger, K. M.
dc.authorsophosHeppner, K.
dc.authorsophosHeiman, M. L.
dc.authorsophosHolsen, L.
dc.authorsophosHolst, B.
dc.authorsophosInui, A.
dc.authorsophosJansson, J. O.
dc.authorsophosKirchner, H.
dc.authorsophosKorbonits, M.
dc.authorsophosLaferrere, B.
dc.authorsophosLeRoux, C. W.
dc.authorsophosLopez, M.
dc.authorsophosMorin, S.
dc.authorsophosNakazato, M.
dc.authorsophosNass, R.
dc.authorsophosPerez-Tilve, D.
dc.authorsophosPfluger, P. T.
dc.authorsophosSchwartz, T. W.
dc.authorsophosSeeley, R. J.
dc.authorsophosSleeman, M.
dc.authorsophosSun, Y.
dc.authorsophosSussel, L.
dc.authorsophosTong, J.
dc.authorsophosThorner, M. O.
dc.authorsophosvan der Lely, A. J.
dc.authorsophosvan der Ploeg, L. H. T.
dc.authorsophosZigman, J. M.
dc.authorsophosKojima, M.
dc.authorsophosKangawa, K.
dc.authorsophosSmith, R. G.
dc.authorsophosHorvath, T.
dc.authorsophosTschop, M. H.
dc.identifier.doi10.1016/j.molmet.2015.03.005
dc.identifier.isi367439600001
dc.identifier.pmid26042199
dc.identifier.sophos19292
dc.issue.number6
dc.journal.titleMolecular metabolism
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago - Complexo Hospitalario Universitario de Santiago::Endocrinoloxía
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago::IDIS.- Instituto de investigaciones sanitarias de Santiago
dc.page.initial437
dc.page.final460
dc.rights.accessRightsopenAccess
dc.typesophosArtículo de Revisión
dc.volume.number4


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