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dc.contributor.authorBarja Fernández, Silvia
dc.contributor.authorFolgueira Cobos, Cintia
dc.contributor.authorCastelao Taboada, Cecilia
dc.contributor.authorLeis Trabazo, María Rosaura 
dc.contributor.authorCasanueva Freijo, Felipe 
dc.date.accessioned2017-06-07T07:34:39Z
dc.date.available2017-06-07T07:34:39Z
dc.date.issued2015
dc.identifier.issn1687-6121
dc.identifier.urihttp://hdl.handle.net/20.500.11940/8146
dc.description.abstractObesity is nowadays a public health problem both in the industrialized world and developing countries. The different treatments to fight against obesity are not very successful with the exception of gastric surgery. The mechanism behind the achievement of this procedure remains unclear although the modifications in the pattern of gastrointestinal hormones production appear to be responsible for the beneficial effect. The gastrointestinal tract has emerged in the last time as an endocrine organ in charge of response to the different stimulus related to nutritional status by the modulation of more than 30 signals acting at central level to modulate food intake and body weight. The production of some of these gastric derived signals has been proved to be altered in obesity (ghrelin, CCK, and GLP-1). In fact, bariatric surgery modifies the production of both gastrointestinal and adipose tissue peripheral signals beyond the gut microbiota composition. Through this paper the main peripheral signals altered in obesity will be reviewed together with their modifications after bariatric surgery.
dc.language.isoeng
dc.rightsAtribución 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titlePeripheral signals mediate the beneficial effects of gastric surgery in obesity
dc.typeArtigoes
dc.authorsophosBarja-Fernández, S.
dc.authorsophosFolgueira, C.
dc.authorsophosCastelao, C.
dc.authorsophosLeis, R.
dc.authorsophosCasanueva, F. F.
dc.authorsophosSeoane, L. M.
dc.identifier.doi10.1155/2015/560938
dc.identifier.isi353514400001
dc.identifier.sophos19490
dc.issue.number560938
dc.journal.titleGastroenterology Research and Practice
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago - Complexo Hospitalario Universitario de Santiago::Endocrinoloxía
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago - Complexo Hospitalario Universitario de Santiago::Pediatría
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago::IDIS.- Instituto de investigaciones sanitarias de Santiago
dc.rights.accessRightsopenAccess
dc.typesophosArtículo de Revisión
dc.volume.number2015


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Atribución 4.0 Internacional
Except where otherwise noted, this item's license is described as Atribución 4.0 Internacional