'Infertile' studies on mitochondrial DNA variation in asthenozoospermic Tunisian men
Identificadores
Identificadores
Visualización o descarga de ficheros
Visualización o descarga de ficheros
Fecha de publicación
2016Título de revista
Biochemistry and Biophysics Reports
Tipo de contenido
Artigo
DeCS
astenozoospermia | biofísica | bioquímica | ADNMeSH
Biophysics | Asthenozoospermia | Biochemistry | DNAResumen
We reviewed five studies undertaken by the same research group on the possible links between mitochondrial DNA (mtDNA) variation and asthenozoospermia, all carried out on Tunisian men. A thorough assessment of these articles reveals that all five studies were carried out on virtually the same cohort of patients, although this information was concealed by the authors. Thus, the results were 'sliced' in order to unjustifiably maximize the number of publications. In addition, a phylogenetic analysis of their data indicates that the reported results are notably incomplete and deficient. Overall, contrary to the original claims, the association of mtDNA variants with asthenozoospermia finds no support on this saga on Tunisian infertile men.
El ítem tiene asociados los siguientes ficheros de licencia: