X chromosome genetic data in a Spanish children cohort, dataset description and analysis pipeline
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Identificadores
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Visualización o descarga de ficheros
Fecha de publicación
2019Título de revista
Scientific Data
Tipo de contenido
Artigo
DeCS
fenotipo | obesidad pediátrica | genotipo | cromosomas | frecuencia génica | humanos | sobrepesoMeSH
Humans | Phenotype | Chromosomes | Pediatric Obesity | Genotype | Gene Frequency | OverweightResumen
X chromosome genetic variation has been proposed as a potential source of missing heritability for many complex diseases, including obesity. Currently, there is a lack of public available genetic datasets incorporating X chromosome genotype data. Although several X chromosome-specific statistics have been developed, there is also a lack of readily available implementations for routine analysis. Here, we aimed: (1) to make public and describe a dataset incorporating phenotype and X chromosome genotype data from a cohort of 915 normal-weight, overweight and obese children, and (2) to deeply describe a whole implementation of the special X chromosome analytic process in genetics. Datasets and pipelines like this are crucial to get familiar with the steps in which X chromosome requires special attention and may raise awareness of the importance of this genomic region.