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X chromosome genetic data in a Spanish children cohort, dataset description and analysis pipeline
dc.contributor.author | Anguita-Ruiz, A. | |
dc.contributor.author | Plaza-Diaz, J. | |
dc.contributor.author | Ruiz-Ojeda, F. J. | |
dc.contributor.author | Rupérez, A. I. | |
dc.contributor.author | Leis Trabazo, María Rosaura | |
dc.contributor.author | Bueno, G. | |
dc.contributor.author | Gil-Campos, M. | |
dc.contributor.author | Vázquez Cobela, Rocio | |
dc.contributor.author | Cañete, R. | |
dc.contributor.author | Moreno, L. A. | |
dc.contributor.author | Gil, Á | |
dc.contributor.author | Aguilera, C. M. | |
dc.date.accessioned | 2021-09-29T12:42:46Z | |
dc.date.available | 2021-09-29T12:42:46Z | |
dc.date.issued | 2019 | |
dc.identifier.issn | 2052-4463 | |
dc.identifier.other | https://www.ncbi.nlm.nih.gov/pubmed/31332195 | es |
dc.identifier.uri | http://hdl.handle.net/20.500.11940/15370 | |
dc.description.abstract | X chromosome genetic variation has been proposed as a potential source of missing heritability for many complex diseases, including obesity. Currently, there is a lack of public available genetic datasets incorporating X chromosome genotype data. Although several X chromosome-specific statistics have been developed, there is also a lack of readily available implementations for routine analysis. Here, we aimed: (1) to make public and describe a dataset incorporating phenotype and X chromosome genotype data from a cohort of 915 normal-weight, overweight and obese children, and (2) to deeply describe a whole implementation of the special X chromosome analytic process in genetics. Datasets and pipelines like this are crucial to get familiar with the steps in which X chromosome requires special attention and may raise awareness of the importance of this genomic region. | en |
dc.language.iso | eng | |
dc.rights | Atribución 4.0 Internacional | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject.mesh | Humans | * |
dc.subject.mesh | Phenotype | * |
dc.subject.mesh | Chromosomes | * |
dc.subject.mesh | Pediatric Obesity | * |
dc.subject.mesh | Genotype | * |
dc.subject.mesh | Gene Frequency | * |
dc.subject.mesh | Overweight | * |
dc.title | X chromosome genetic data in a Spanish children cohort, dataset description and analysis pipeline | es |
dc.type | Artigo | es |
dc.authorsophos | Anguita-Ruiz, A. | |
dc.authorsophos | Plaza-Diaz, J. | |
dc.authorsophos | Ruiz-Ojeda, F. J. | |
dc.authorsophos | Rupérez, A. I. | |
dc.authorsophos | Leis, R. | |
dc.authorsophos | Bueno, G. | |
dc.authorsophos | Gil-Campos, M. | |
dc.authorsophos | Vázquez-Cobela, R. | |
dc.authorsophos | Cañete, R. | |
dc.authorsophos | Moreno, L. A. | |
dc.authorsophos | Gil, Á | |
dc.authorsophos | Aguilera, C. M. | |
dc.identifier.doi | 10.1038/s41597-019-0109-3 | |
dc.identifier.pmid | 31332195 | |
dc.identifier.sophos | 30550 | |
dc.issue.number | 1 | es |
dc.journal.title | Scientific Data | es |
dc.organization | Servizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Pediatría | |
dc.organization | Servizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS) | |
dc.page.initial | 130 | es |
dc.relation.publisherversion | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646348/pdf/41597_2019_Article_109.pdf | |
dc.rights.accessRights | openAccess | |
dc.subject.decs | fenotipo | * |
dc.subject.decs | obesidad pediátrica | * |
dc.subject.decs | genotipo | * |
dc.subject.decs | cromosomas | * |
dc.subject.decs | frecuencia génica | * |
dc.subject.decs | humanos | * |
dc.subject.decs | sobrepeso | * |
dc.subject.keyword | CHUS | |
dc.subject.keyword | IDIS | |
dc.typefides | Artículo Científico (incluye Original, Original breve, Revisión Sistemática y Meta-análisis) | |
dc.typesophos | Artículo Original | |
dc.volume.number | 6 | es |