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dc.contributor.authorAnguita-Ruiz, A.
dc.contributor.authorPlaza-Diaz, J.
dc.contributor.authorRuiz-Ojeda, F. J.
dc.contributor.authorRupérez, A. I.
dc.contributor.authorLeis Trabazo, María Rosaura 
dc.contributor.authorBueno, G.
dc.contributor.authorGil-Campos, M.
dc.contributor.authorVázquez Cobela, Rocio
dc.contributor.authorCañete, R.
dc.contributor.authorMoreno, L. A.
dc.contributor.authorGil, Á
dc.contributor.authorAguilera, C. M.
dc.date.accessioned2021-09-29T12:42:46Z
dc.date.available2021-09-29T12:42:46Z
dc.date.issued2019
dc.identifier.issn2052-4463
dc.identifier.otherhttps://www.ncbi.nlm.nih.gov/pubmed/31332195es
dc.identifier.urihttp://hdl.handle.net/20.500.11940/15370
dc.description.abstractX chromosome genetic variation has been proposed as a potential source of missing heritability for many complex diseases, including obesity. Currently, there is a lack of public available genetic datasets incorporating X chromosome genotype data. Although several X chromosome-specific statistics have been developed, there is also a lack of readily available implementations for routine analysis. Here, we aimed: (1) to make public and describe a dataset incorporating phenotype and X chromosome genotype data from a cohort of 915 normal-weight, overweight and obese children, and (2) to deeply describe a whole implementation of the special X chromosome analytic process in genetics. Datasets and pipelines like this are crucial to get familiar with the steps in which X chromosome requires special attention and may raise awareness of the importance of this genomic region.en
dc.language.isoeng
dc.rightsAtribución 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.meshHumans*
dc.subject.meshPhenotype*
dc.subject.meshChromosomes*
dc.subject.meshPediatric Obesity*
dc.subject.meshGenotype*
dc.subject.meshGene Frequency*
dc.subject.meshOverweight*
dc.titleX chromosome genetic data in a Spanish children cohort, dataset description and analysis pipelinees
dc.typeArtigoes
dc.authorsophosAnguita-Ruiz, A.
dc.authorsophosPlaza-Diaz, J.
dc.authorsophosRuiz-Ojeda, F. J.
dc.authorsophosRupérez, A. I.
dc.authorsophosLeis, R.
dc.authorsophosBueno, G.
dc.authorsophosGil-Campos, M.
dc.authorsophosVázquez-Cobela, R.
dc.authorsophosCañete, R.
dc.authorsophosMoreno, L. A.
dc.authorsophosGil, Á
dc.authorsophosAguilera, C. M.
dc.identifier.doi10.1038/s41597-019-0109-3
dc.identifier.pmid31332195
dc.identifier.sophos30550
dc.issue.number1es
dc.journal.titleScientific Dataes
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::EOXI de Santiago de Compostela - Complexo Hospitalario Universitario de Santiago de Compostela::Pediatría
dc.organizationServizo Galego de Saúde::Estrutura de Xestión Integrada (EOXI)::Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS)
dc.page.initial130es
dc.relation.publisherversionhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646348/pdf/41597_2019_Article_109.pdf
dc.rights.accessRightsopenAccess
dc.subject.decsfenotipo*
dc.subject.decsobesidad pediátrica*
dc.subject.decsgenotipo*
dc.subject.decscromosomas*
dc.subject.decsfrecuencia génica*
dc.subject.decshumanos*
dc.subject.decssobrepeso*
dc.subject.keywordCHUS
dc.subject.keywordIDIS
dc.typefidesArtículo Científico (incluye Original, Original breve, Revisión Sistemática y Meta-análisis)
dc.typesophosArtículo Original
dc.volume.number6es


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