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dc.contributor.authorOtero Millán, Luis
dc.contributor.authorBea Mascato, Brais
dc.contributor.authorLegido Soto, Jose Luis
dc.contributor.authorMartínez Lopez de Castro, Noemi 
dc.contributor.authorLago Rivero, Natividad 
dc.date.accessioned2024-05-27T08:12:16Z
dc.date.available2024-05-27T08:12:16Z
dc.date.issued2024-02
dc.identifier.issn1999-4923
dc.identifier.otherhttps://pubmed.ncbi.nlm.nih.gov/38543210/es
dc.identifier.otherhttps://www.webofscience.com/wos/woscc/full-record/WOS:001192760700001es
dc.identifier.urihttp://hdl.handle.net/20.500.11940/18782
dc.description.abstract[ENG] (1) Background: parenteral nutrition (PN) solutions are an extremely complex mixture. It is composed of a multitude of chemical elements that can give rise to a large number of interactions that condition its stability and safety. The aim of this study was to evaluate the stability of PN solutions for preterm infants. (2) Methods: eight samples were prepared according to the protocol for prescribing PN in preterm infants. Samples PN1-PN7 had the normal progression of macronutrients and standard amounts of micronutrients for a 1 kg preterm infant. The PN8 sample had a high concentration of electrolytes, with the idea of forcing stability limits. Samples were stored both at room temperature and under refrigeration. Measurements of globule size, pH, density, and viscosity were performed in both storage protocols on different days after processing. (3) Results: the changes in the composition of the samples did not affect the evolution of the stability at the different measurement times and temperatures. Viscosity was affected by the compositional changes made in the PN samples, but no alterations due to time or temperature were observed. Density and pH remained stable, without significant changes due to time, storage temperature, or different composition. (4) Conclusion: all samples remained stable during the study period and did not undergo significant alterations due to compositional changes or different experimental conditions.es
dc.language.isoenges
dc.subject.meshCritical Care *
dc.subject.meshInfant Nutritional Physiological Phenomena *
dc.titleEvaluation of the Stability of Newborn Hospital Parenteral Nutrition Solutionses
dc.typeArtigoes
dc.identifier.doi10.3390/pharmaceutics16030316
dc.identifier.pmid38543210
dc.issue.number3es
dc.journal.titlePharmaceuticses
dc.organizationServizo Galego de Saúde::Áreas Sanitarias (A.S.)::Área Sanitaria de Vigo - Complexo Hospitalario Universitario de Vigo::Farmaciaes
dc.organizationServizo Galego de Saúde::Áreas Sanitarias (A.S.)::Instituto de Investigación Sanitaria Galicia Sur ((IISGS)es
dc.page.initial316es
dc.relation.publisherversionhttps://www.mdpi.com/1999-4923/16/3/316es
dc.rights.accessRightsopenAccesses
dc.subject.decsasistencia del enfermo crítico *
dc.subject.decsfenómenos fisiológicos nutricionales del lactante *
dc.subject.keywordestabilidad físico-químicaes
dc.subject.keywordCHUVIes
dc.subject.keywordIISGSes
dc.typefidesArtigo Científico (inclue Orixinal, Orixinal breve, Revisión Sistemática e Meta-análisis)es
dc.typesophosArtículo Originales
dc.volume.number16es


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